A phase II study of iproplatin in advanced or metastatic stomach cancer. The EORTC Early Clinical Trial Group.

Response to neoadjuvant chemotherapy in locally advanced gastric and gastroesophageal cancer: Phase II clinical trial

Background: Gastric cancer is an important health problem across the world. Chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. The purpose of this investigation was evaluation of response and tolerability to neoadjuvant EOX regimen in locoregionally advanced gastric cancer. Materials and Methods: patients with locoregionally adv...

Short Communication Fotemustine in Patients with Advanced Gastric Cancer, a Phase II Trial From the EORTC-GITCCG (European Organization for Research and Treatment of Cancer, Gastrointestinal Tract Cancer Cooperative Group)

Short Communication Fotemustine in Patients with Advanced Gastric Cancer, a Phase II Trial From the EORTC-GITCCG (European Organization for Research and Treatment of Cancer, Gastrointestinal Tract Cancer Cooperative Group)

Integration of Trastuzumab, with or without Pertuzumab, into Perioperative Chemotherapy of HER2- Positive Stomach Cancer: The INNOVATION Trial (EORTC-1203-GITCG).

This international, randomized phase II trial is a collaboration between EORTC (leading group), the Korean Cancer Study Group, who committed to recruit 50% of the patients, and the Dutch Upper GI Cancer Group. It has been designed to assess the impact of integrating trastuzumab alone and the combination of trastuzumab and pertuzumab in the perioperative treatment of resectable, HER-2 positive a...

Phase IIa Clinical Trial of Trans-1-Amino-3-18F-Fluoro- Cyclobutane Carboxylic Acid in Metastatic Prostate Cancer

Objective(s): We performed a phase IIa clinical trial of trans-1-amino-3-18Ffluoro-cyclobutane carboxylic acid (anti-18F-FACBC), a synthetic amino acid analog for PET, in patients with metastatic prostate cancer. Methods: The study subjects consisted of 10 untreated prostate cancer patients having lymph node and/or bone metastasis. Five patients underwent whole-body PET 5 and 30 min after intra...